CalbicansSC5314 Candida albicans SC5314
Top track: the genes MATPredict modelled at the MAT locus. Bottom track: every FungiDB gene in the same region (locus span, shaded, plus 5 kb each side). A FungiDB gene is green when a MATPredict gene overlaps it on the same strand. Hover a gene for its coordinates and product; FungiDB gene IDs link to fungidb.org.
core MAT geneflanking conserved geneotherFungiDB gene matched by MATPredict
Ascomycota_MTL_0: A Ascomycota:MTL, confidence high, Ca22chr5A_C_albicans_SC5314:393493-402144
| MATPredict gene | Role | Coordinates | Verdict | FungiDB gene | FungiDB product | Why |
|---|---|---|---|---|---|---|
| MTLA1 | core_MAT | 393493-394455 - | annotated | C5_01740C_A MTLA1 | Homeodomain protein of the MTLa mating type locus, a1 and alpha2 together repress white-opaque switching and mating (an opaque-specific process), a/alpha mating type may increase virulence by competitive advantage, Spider biofilm induced | C5_01740C_A covers 100% of it on the same strand |
| MTLA2 | core_MAT | 394560-395220 - | annotated | C5_01750C_A MTLA2 | Master regulator (activator) of a-type mating, has HMG domain, which is predicted to bind DNA, gene has intron, not related to S. cerevisiae MATa2, a/alpha mating type may increase virulence, provides competitive advantage | C5_01750C_A covers 100% of it on the same strand |
| PIK1 | flanking_variable | 395335-398205 - | annotated | C5_01760C_A PIKA | Phosphatidylinositol 4-kinase, controls levels of phosphatidylinositol-4-phosphate (PI(4)P) in the Golgi, non-sex gene located in MTLa mating-type-like locus, nonidentical gene encoding PI(4)P kinase, PIKALPHA, located in MTLalpha locus | C5_01760C_A covers 100% of it on the same strand |
| OBP1 | flanking_variable | 398770-400071 - | annotated | C5_01770C_A OBPA | Similar to oxysterol binding protein, non-sex gene located within the MTLa mating-type-like locus, Plc1p-regulated | C5_01770C_A covers 100% of it on the same strand |
| PAP1 | flanking_variable | 400477-402144 + | annotated | C5_01780W_A PAP1 | Poly(A) polymerase, likely involved in mRNA polyadenylation, PAP is inhibited by parnafungin antifungals, non-sex gene located within the MTLa mating-type-like locus | C5_01780W_A covers 100% of it on the same strand |